It’s true that React JSX needs transpilation and Angular (if used with the suggested language, TS) needs compilation. Let’s not forget Marko, Vue, Riot, etc. But the future with ES6 modules in place doesn’t necessarily look the same. Debugging transpiled/compiled code is always going to be more complicated and if the runtime gain of minifiying the JS files leads to saving less than 50KB, developers would probably not bother in an era where the average page size is over 1.4MB.